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Published: Jun 11, 2022 License: MIT

Directories

Path Synopsis
analysis
dbgenes
Package dbgenes generates a list of genes in sequence database
Package dbgenes generates a list of genes in sequence database
assessment
bait/gradient
Package gradient draws a similarity gradient for baits.
Package gradient draws a similarity gradient for baits.
controls/preys
Package preys outputs statistics on prey proteins in controls.
Package preys outputs statistics on prey proteins in controls.
countgo
Package countgo count the number of genes with a GO term.
Package countgo count the number of genes with a GO term.
goenrich
Package goenrich finds enriched GO terms via gProfiler
Package goenrich finds enriched GO terms via gProfiler
hydropathy
Package hydropathy calculates the average hydropathy of proteins sequences
Package hydropathy calculates the average hydropathy of proteins sequences
localization/evaluate
Package evaluate localizes preys using LBA
Package evaluate localizes preys using LBA
localization/nmfsafe
Package nmfsafe checks NMF and SAFE localizations for agreement.
Package nmfsafe checks NMF and SAFE localizations for agreement.
localization/prediction
Package prediction calculates a prediction score for each prey.
Package prediction calculates a prediction score for each prey.
localization/recovered
Package recovered reports the number of genes seen in a specific compartment.
Package recovered reports the number of genes seen in a specific compartment.
transmembrane
Package transmembrane reports the orientation evidence for transmembrane preys.
Package transmembrane reports the orientation evidence for transmembrane preys.
enrichment
genes
Package genes performs a GO enrichment on a list of genes.
Package genes performs a GO enrichment on a list of genes.
heatmap
Package heatmap creates a heat map to display enriched regions across compartments.
Package heatmap creates a heat map to display enriched regions across compartments.
interaction
knownbyrank
Package knownbyrank calculates the proportion of known interactors for the Nth best prey across baits in a SAINT report
Package knownbyrank calculates the proportion of known interactors for the Nth best prey across baits in a SAINT report
rankaverage
Package rankaverage calculates the average interaction ranks for supplied prey list
Package rankaverage calculates the average interaction ranks for supplied prey list
rankmetrics
Package rankmetrics calculates prey metrics for each prey interaction rank.
Package rankmetrics calculates prey metrics for each prey interaction rank.
lba
Package lba is for localizing prey genes.
Package lba is for localizing prey genes.
enrichment
Package enrichment performs GO enrichments for LBA.
Package enrichment performs GO enrichments for LBA.
localize
Package localize localizes preys using LBA
Package localize localizes preys using LBA
network
correlation
Package correlation creates files for visualizing LBA as a correlation network.
Package correlation creates files for visualizing LBA as a correlation network.
matrix
Package matrix creates files for visualizing LBA as a correlation network.
Package matrix creates files for visualizing LBA as a correlation network.
svg
Package svg creates a network in svg format from NMF or SAFE data.
Package svg creates a network in svg format from NMF or SAFE data.
tsnecytoscape
Package tsnecytoscape generates a Cytoscape network from t-SNE coordinates.
Package tsnecytoscape generates a Cytoscape network from t-SNE coordinates.
nmf
moonlighting
Package moonlighting scores preys localized by NMF for moonlighting in more than one compartment
Package moonlighting scores preys localized by NMF for moonlighting in more than one compartment
robustness
Package robustness assesses the sensitivity of NMF rank assignments
Package robustness assesses the sensitivity of NMF rank assignments
subset
Package subset filters an NMF basis (prey) matrix to only include preys enriched all specified rank.
Package subset filters an NMF basis (prey) matrix to only include preys enriched all specified rank.
uv
Package uv validates the localizations of prey genes not used for defining NMF ranks
Package uv validates the localizations of prey genes not used for defining NMF ranks
isolation
Package isolation calculates percent isolation of each NMF compartment.
Package isolation calculates percent isolation of each NMF compartment.
overlap
Package overlap calculates overlap metrics between two lists of proteins
Package overlap calculates overlap metrics between two lists of proteins
shared
Package shared outputs metrics on the regions found in preys shared by two lists of proteins
Package shared outputs metrics on the regions found in preys shared by two lists of proteins
pkg
cluster
Package cluster clusters a matrix
Package cluster clusters a matrix
function
Package function returns functions defined from input arguments
Package function returns functions defined from input arguments
image/file
Package file has methods for opening and writing to a file for creating images
Package file has methods for opening and writing to a file for creating images
image/svg/heatmap
Package heatmap creates svg files for various image types.
Package heatmap creates svg files for various image types.
localization
Package localization contains functions for assessing localizations
Package localization contains functions for assessing localizations
nmf
Package nmf implements common functions for NMF analysis.
Package nmf implements common functions for NMF analysis.
read/bioplex
Package bioplex reads a Bioplex interaction file
Package bioplex reads a Bioplex interaction file
read/csv
Package csv reads a csv file
Package csv reads a csv file
read/database
Package database reads a fasta database to an array.
Package database reads a fasta database to an array.
read/geneontology
Package geneontology contains functions for reading and parsing Gene Ontology (GO) files.
Package geneontology contains functions for reading and parsing Gene Ontology (GO) files.
read/interactions
Package interactions reads interactions from BioGRID and/or Intact
Package interactions reads interactions from BioGRID and/or Intact
read/matrix
Package matrix reads matrix from txt file.
Package matrix reads matrix from txt file.
read/nmf
Package nmf reads NMF output files and assesses localizations
Package nmf reads NMF output files and assesses localizations
read/pfam
Package pfam reads domain and motif information from a file.
Package pfam reads domain and motif information from a file.
read/safe
Package safe read SAFE output files
Package safe read SAFE output files
read/saint
Package saint reads and parses SAINT-related files.
Package saint reads and parses SAINT-related files.
read/tsne
Package tsne reads t-SNE coordinate file.
Package tsne reads t-SNE coordinate file.
read/uniprot
Package uniprot reads a uniprot database.
Package uniprot reads a uniprot database.
preyprey
subset
Package subset gets a cluster from a prey-prey interactive file.
Package subset gets a cluster from a prey-prey interactive file.
summary
crapome
Package crapome generates a CRAPome matrix from SAINT input files.
Package crapome generates a CRAPome matrix from SAINT input files.
notsignificant
Package notsignificant outputs non significant preys
Package notsignificant outputs non significant preys

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