kinase

Documentation

Index

• type CaDtParams
  • func (kp *CaDtParams) Defaults()
  • func (kp *CaDtParams) Update()
• type CaParams
  • func (kp *CaParams) CurCa(ctime, utime int32, caM, caP, caD *float32)
  • func (kp *CaParams) Defaults()
  • func (kp *CaParams) FmCa(ca float32, caM, caP, caD *float32)
  • func (kp *CaParams) FmSpike(spike float32, caM, caP, caD *float32)
  • func (kp *CaParams) IntFmTime(ctime, utime int32) int32
  • func (kp *CaParams) Update()

Types

type CaDtParams

type CaDtParams struct {
	MTau float32 `` /* 233-byte string literal not displayed */
	PTau float32 `` /* 310-byte string literal not displayed */
	DTau float32 `` /* 300-byte string literal not displayed */
	MDt  float32 `view:"-" json:"-" xml:"-" inactive:"+" desc:"rate = 1 / tau"`
	PDt  float32 `view:"-" json:"-" xml:"-" inactive:"+" desc:"rate = 1 / tau"`
	DDt  float32 `view:"-" json:"-" xml:"-" inactive:"+" desc:"rate = 1 / tau"`
	// contains filtered or unexported fields
}

CaDtParams has rate constants for integrating Ca calcium at different time scales, including final CaP = CaMKII and CaD = DAPK1 timescales for LTP potentiation vs. LTD depression factors.

func (*CaDtParams) Defaults

func (kp *CaDtParams) Defaults()

func (*CaDtParams) Update

func (kp *CaDtParams) Update()

type CaParams

type CaParams struct {
	SpikeG  float32 `` /* 189-byte string literal not displayed */
	UpdtThr float32 `` /* 308-byte string literal not displayed */
	MaxISI  int32   `def:"100" desc:"maximum ISI for integrating in Opt mode -- above that just set to 0"`

	Dt CaDtParams `view:"inline" desc:"time constants for integrating at M, P, and D cascading levels"`
	// contains filtered or unexported fields
}

CaParams has rate constants for integrating spike-driven Ca calcium at different time scales, including final CaP = CaMKII and CaD = DAPK1 timescales for LTP potentiation vs. LTD depression factors.

func (*CaParams) CurCa

func (kp *CaParams) CurCa(ctime, utime int32, caM, caP, caD *float32)

CurCa updates the current Ca* values, dealing with updating for optimized spike-time update versions. ctime is current time in msec, and utime is last update time (-1 if never)

func (*CaParams) Defaults

func (kp *CaParams) Defaults()

func (*CaParams) FmCa

func (kp *CaParams) FmCa(ca float32, caM, caP, caD *float32)

FmCa computes updates to CaM, CaP, CaD from current calcium level. The SpikeG factor is NOT applied to Ca and should be pre-applied as appropriate.

func (*CaParams) FmSpike

func (kp *CaParams) FmSpike(spike float32, caM, caP, caD *float32)

FmSpike computes updates to CaM, CaP, CaD from current spike value. The SpikeG factor determines strength of increase to CaM.

func (*CaParams) IntFmTime

func (kp *CaParams) IntFmTime(ctime, utime int32) int32

IntFmTime returns the interval from current time and last update time, which is -1 if never updated (in which case return is -1)

func (*CaParams) Update

func (kp *CaParams) Update()